Fig. 10
From: Effects of a combination treatment of KD5040 and L-dopa in a mouse model of Parkinson’s disease
Effects of combination treatment on protein expression in the striatum. Representative Western blot images (upper panel) and quantifications (lower panel) of four proteins showing significant differences between groups. Protein analyses of FosB (a), pDARRPP32 (b), pERK (c) and pCREB (d). Western blot analyses showing significantly lower expression levels of FosB, pDARRPP32, pERK, and pCREB after combination treatment. C: control, M: MPTP, K: KD5040, HL: high dose of l -dopa (20 mg/kg). * p < 0.05 vs. control group, ### p < 0.001 and ## p < 0.01 vs. MPTP group, and ††† p < 0.001 vs. each dose of l -dopa