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Table 3 17-Item Hamilton Scale for Depression: Differences between baseline and T1 (after 4 interventions) and T2 (4 weeks after treatment) in the hyperthermic bath group compared to the placebo group (intention-to-treat population;a N = 36)

From: Effects of hyperthermic baths on depression, sleep and heart rate variability in patients with depressive disorder: a randomized clinical pilot trial

  

T1

   

T2

  
 

HTB Group (n = 17)

Placebo Group (n = 19)

P §

Cohen

dc

HTB Group (n = 17)

Placebo Group (n = 19)

P §

Cohen

dc

1HAM-Dtotal score b

4.35 (6.3)

1.21 (3.7)

0.037 *

0.62 [-0.05-1.29]

4.82 (7.3)

3.26 (5.7)

0.238

0.24 [-0.42-0.90]

2HAM-Dinsomnia b

0.94 (1.8)

0.16 (1.0)

0.053

0.55 [-0.11-1.22]

0.88 (1.7)

0.58 (1.8)

0.306

0.17 [-0.49-0.83]

2HAM-Dmood b

2.35 (3.2)

0.84 (2.2)

0.054

0.55 [-0.12-1.22]

2.82 (3.8)

1.74 (2.5)

0.156

0.33 [-0.33-0.99]

2HAM-Dsomatic b

0.59 (1.0)

0.21 (1.4)

0.182

0.31 [-0.35-0.97]

0.71 (1.4)

0.58 (1.4)

0.390

0.09 [-0.56-0.75]

  1. Abbreviations: HTB hyperthermic baths, HAM-D Hamilton Scale for Depression
  2. aThe intention-to-treat analysis used last-observation-carried-forward
  3. bIndicates differences between HTB and placebo in the change from T0 to T1/T2 to each patient’s own end point for the change in depression rating
  4. cComputed as the difference between the means, M2 – M1, divided by the pooled standard deviation, sigma (σpooled) of both groups. [95% confidence interval]
  5. Data are shown as mean and standard deviation (SD)
  6. §1-tailed t test
  7. 1Primary outcome
  8. 2Secondary outcome
  9. *P < .05