Table 1 The effect of rhubarb its absorbed compound rhein on brain tissues of TBI rats in reduced and oxidized glutathione levels

Sham

100.23 ± 7.09

27.29 ± 3.54

3.67 ± 0.65

95.57 ± 8.54

26.98 ± 2.14

3.54 ± 0.33

97.24 ± 8.03

29.34 ± 1.88

3.31 ± 0.29

Vehicle

70.12 ± 6.95^#

50.61 ± 4.61^#

1.39 ± 0.11^#

69.22 ± 7.17^#

52.14 ± 3.67^#

1.33 ± 0.09^#

62.71 ± 6.24^#

48.87 ± 3.96^#

1.28 ± 0.22^#

3 g/kg Rhubarb

71.17 ± 6.25

42.81 ± 4.77^*

1.66 ± 0.14^*

75.97 ± 6.25^*

49.36 ± 4.02

1.54 ± 0.22

74.02 ± 7.14^△

39.57 ± 4.43^*

1.87 ± 0.29^*

6 g/kg Rhubarb

72.14 ± 7.47

38.21 ± 3.31^△

1.89 ± 0.17^△

79.64 ± 8.24^*

48.74 ± 3.49^*

1.63 ± 0.16^*

83.81 ± 8.16^△

32.88 ± 2.82^△

2.55 ± 0.27^△

12 g/kg Rhubarb

85.62 ± 7.15^△

35.78 ± 4.11^△

2.39 ± 0.27^△

89.27 ± 8.07^△

33.96 ± 3.51^△

2.63 ± 0.29^△

92.55 ± 8.43^△

31.34 ± 2.5^△

2.95 ± 0.32^△

12 mg/kg Rhein

78.69 ± 7.06^△

34.28 ± 3.84^△

2.30 ± 0.25^△

93.74 ± 8.84^△

41.44 ± 3.87^△

2.26 ± 0.18^△

90.87 ± 8.31^△

35.35 ± 3.47^△

2.57 ± 0.18^△