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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Withania somnifera leaf alleviates cognitive dysfunction by enhancing hippocampal plasticity in high fat diet induced obesity model

Fig. 4

Quantitative mRNA expression analysis of genes involved in BDNF mediated synaptic plasticity and cell survival. Representative immunoblots (a) and densitometric analysis (b) of markers involved in cell survival such as Akt-1, c-Jun and c-fos in hippocampus and pyriform cortex regions of rat brain. Quantitative mRNA expression of BDNF, TRKB, RAS, PI3K, Akt-1, c-Jun and c-fos in hippocampus (c) and pyriform cortex (d) regions of rat brain among the four groups (n = 3 for each group).*p < 0.05 LFD vs. HFD, LFDE and HFDE rats, # p < 0.05 LFDE vs. HFD rats, £ p < 0.05 LFDE vs. HFDE rats, p < 0.05 HFDE vs. HFD rats, $signifies highly significant levels. Holm-sidak test after one-way ANOVA

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