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Table 4 In vivo antidiarrheal indices of 80ME and solvent fractions of the leaves of Myrtus communis

From: Evaluation of the antidiarrheal activity of the leaf extracts of Myrtus communis Linn (Myrtaceae) in mice model

Dose (mg/kg) Delay in defecation (time of onset in min, Dfreq) (%) Gut meal travel distance (Gmeq) (%) Purging frequency in number of wet stools (%) In vivo antidiarrheal index (ADI)
Control ------- ------- ------- -------
80ME 100 43.04 33.54 42.58 39.47
80ME 200 89.12 46.12 62.52 63.58
80ME 400 126.72 62.31 74.96 83.96
Loperamide 3 110.64 59.61 72.56 78.22
Control ------- ------ ------ -----
CF 200 53.84 27.99 38.46 38.69
CF 300 75.25 35.11 51.23 51.34
CF 400 89.59 44.86 58.92 61.87
Loperamide 3 106.85 60.56 74.31 78.34
Control ------ ------ ------ ------
MF 200 50.48 21.24 31.07 32.18
MF 300 96.16 35.85 48.93 55.25
MF 400 124.29 47.54 62.67 71.81
Loperamide 3 140.63 61.47 75.56 86.76
Control ------- ------- -------- -------
AF 200 2.16 4.81 8.93 4.53
AF 300 11.54 12.58 15.60 13.13
AF 400 16.83 20.73 24.40 20.42
AF 800 94.24 38.61 53.33 57.89
loperamide 140.63 61.47 75.56 86.76
  1. 80ME = 80% methanol extract, CF = chloroform fraction, MF = methanol fraction, AF = aqueous fraction
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