Fig. 8

Histopathology pictures of synovial membrane and cartilage. First column (a1-6) showing photographs of synovium stained with H and E and further are photographs of cartilage stained with H and E (b1-6), Masson’s trichome (c1-6) and safranin-O (d1-6) respectively. Last column (e1-6) showing photographs of whole knee joint stained with H and E. HC: Healthy control, OAC: Osteoarthritic control, DICLO: Positive control, OA-F2L: OA-F2 at 135 mg/kg b. wt., OA-F2M: OA-F2 at 270 mg/kg b. wt., OA-F2H: OA-F2 at 540 mg/kg b. wt., H and E: hematoxyline and eosin