Acthaside: a new chromone derivative from Acacia ataxacantha and its biological activities

Table 2 Minimum inhibitory concentration (MIC) and Minimum bactericidal and fungicidal concentrations (MBC, MFC) of acthaside (μg/ml) from A. ataxacantha against microorganisms

	Minimum inhibitory concentrations (μg/ml)
Microorganisms^a	Gram (+) bacteria				Gram (-) bacteria	Yeast
Microorganisms^a	S.a	S.a.m.r	S. ep	E.f	P.a	C. a
Isolated compound^b	50	50	25	50	50	25
Gentamicin	0.39	0.39	0.78	0.39	0.78	Nt
Fluconazole	Nt	Nt	Nt	Nt	Nt	0.78
Minimum bactericidal and fungicidal (μg/ml)
Isolated compound^b	50	50	25	50	50	25
Gentamicin	0.78	1.56	1.56	0.78	1.56	Nt
Fluconazole	Nt	Nt	Nt	Nt	Nt	1.56
MIC index
Isolated compound	1	1	1	1	1	1
Gentamicin	2	4	2	2	2	Nt
Fluconazole	Nt	Nt	Nt	Nt	Nt	2

^a S. a : Staphylococcus aureus; S.a.m.r : Staphylococcus aureus methicillin resitant; S.ep : Staphylococcus epidermidis; E. f: Enterococcus faecalis; P. a: Pseudomonas aeruginosa; C. a: Candida albicans. Nt not tested
^bisolated compound: 7-hydroxy-2-methyl-6-[β-galactopyranosyl-propyl]-4H-Chromen-4-one (acthaside)

ISSN: 2662-7671