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Table 1 Inhibition parameters (MIC, MBC) of compounds 1–3 and reference antibacterial drugs

From: Antibacterial and cytotoxic cytochalasins from the endophytic fungus Phomopsis sp. harbored in Garcinia kola (Heckel) nut

Antibacterial activity (MIC and MBC in μg/mL)
Compounds Inhibition parameters V. cholerae SG24 V. cholerae CO6 V. cholerae NB2 V. cholerae PC2 S. flexneri SDINT S. aureus ATCC 25923
1 MIC >512 512 512 >512 128 128
MBC >512 512 512 >512 128 128
MBC/MIC / 1 1 / 1 1
2 MIC >512 512 512 256 128 256
MBC >512 512 512 256 128 256
MBC/MIC / 1 1 1 1 1
3 MIC >512 512 512 >512 128 512
MBC >512 512 512 >512 128 512
MBC/MIC / 1 1 / 1 1
Tetracycline MIC 0.50 2 0.50 0.50 16 16
MBC 1 8 2 1 32 32
MBC/MIC 2 4 4 2 2 2
Ampicillin MIC 16 16 >512 >512 >512 16
MBC 16 16 >512 >512 >512 16
MBC/MIC 1 1 / / / 1
  1. / not determined; MIC Minimum Inhibitory Concentration; MBC Minimum Bactericidal Concentration
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