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Table 4 Antimutagenic effects of 31 methanol plant extracts in S. typhimurium TA98 and TA100 tester strains

From: The correlation between antimutagenic activity and total phenolic content of extracts of 31 plant species with high antioxidant activity

Sample #

Conc.(mg/ml)

TA 98

TA 100

5

0.5

0.05

5

0.5

0.05

1

180.00 ± 34.59

[20.68 ± 2.27]

253.67 ± 16.65

[−16.44 ± 1.62]

260.67 ± 15.04

[−19.99 ± 3.68]

662.67 ± 8.09

[39.09 ± 3.14]

877.33 ± 15.18

[14.28 ± 2.58]

1001.33 ± 6.43

[−0.21 ± 0.78]

2

227.10 ± 24.31

[-3.22±2.44]

226.00 ± 11.68

[−2.71 ± 2.23]

233.67 ± 10.01

[−6.27 ± 0.37]

673.67 ± 13.87

[37.79 ± 1.68]

961.67 ± 4.58

[4.54 ± 0.56]

1000.67 ± 20.74

[0.08 ± 1.38]

3

20.4.67±24.09

[8.48±2.39]

199.67 ± 16.86

[11.02 ± 1.06]

190.33 ± 18.15

[15.60 ± 3.47]

657.00 ± 11.36

[39.67 ± 1.38]

760.67 ± 12.67

[29.40 ± 1.54]

940.67 ± 12.50

[6.73 ± 1.54]

4

343.00±32.69

[-62.26±13.47]

200.67 ± 36.35

[10.52 ± 1.49]

227.67 ± 35.81

[−3.22 ± 1.47]

948.67 ± 29.40

[4.66 ± 4.82]

802.00 ± 24.64

[18.01 ± 2.40]

690.00 ± 16.09

32.43 ± 1.57]

5

417.67±14.19

[-97.89±5.84]

347.67 ± 36.07

[−64.30 ± 14.86]

243.00 ± 5.57

[−11.36 ± 2.29]

955.00 ± 10.15

[9.89 ± 0.99]

760.00 ± 26.63

[38.88 ± 2.60]

803.55 ± 34.075

[24.99 ± 3.32]

6

190.67±24.09

[15.61 ± 9.92]

177.67 ± 17.78

[22.23 ± 7.32]

159.33 ± 30.83

[31.39 ± 12.70]

518.00 ± 26.51

[52.19 ± 4.53]

613.67 ± 17.52

[45.50 ± 1.71]

635.33 ± 12.66

[42.39 ± 1.23]

Solvent blank

24.2 ± 5.63

  

134.40 ± 3.53

  

Positive control

220.67 ± 10.97

  

1001.00 ± 17.43

  

7

230.67 ± 21.50

[−11.33 ± 1.08]

110.00 ± 7.94

[53.39 ± 4.00]

182.67 ± 8.33

[14.56 ± 4.20]

995.00 ± 29.87

[15.52 ± 2.35]

903.00 ± 14.53

[24.35 ± 11.42]

1116.67 ± 8.54

[3.79 ± 6.72]

8

285.33 ± 29.50

[−40.99 ± 1.49]

156.33 ± 16.44

[28.59 ± 2.84]

157.67 ± 9.45

[28.05 ± 4.78]

843.33 ± 9.45

[30.14 ± 7.43]

733.33 ± 12.67

[40.74 ± 9.95]

826.67 ± 10.02

[31.75 ± 7.87]

9

170.67 ± 10.69

[2.03 ± 5.39]

164.67 ± 22.68

[24.27 ± 11.40]

176.33 ± 31.66

[17.80 ± 5.79]

853.33 ± 4.04

[29.17 ± 3.18]

1023.00 ± 11.36

[12.82 ± 8.93]

1262.67 ± 10.50

[−10.28 ± 8.26]

10

347.67 ± 20.21

[−74.43 ± 1.76]

232.67 ± 16.26

[−12.40 ± 1.17]

219.67 ± 10.50

[5.39 ± 7.57]

1686.67 ± 9.74

[−51.15 ± 17.75]

1330.00 ± 18.77

[−16.77 ± 6.70]

1253.33 ± 15.14

[−9.38 ± 5.40]

11

252.67 ± 8.14

[−23.19 ± 5.87]

247.67 ± 23.75

[−20.49 ± 1.71]

210.00 ± 14.80

[−0.92 ± 1.07]

1110.00 ± 21.00

[4.43 ± 7.49]

1243.33 ± 4.04

[−8342 ± 1.44]

1377.33 ± 13.11

[−21.33 ± 4.68]

12

180.00 ± 8.88

[15.64 ± 6.41]

230.00 ± 18.52

[−27.51 ± 13.35]

223.67 ± 26.10

[−7.55 ± 1.88]

681.40 ± 15.03

[45.75 ± 11.43]

873.33 ± 3.05

[27.25 ± 1.09]

1006.67 ± 10.21

[14.39 ± 3.64]

Solvent blank

23.60 ± 2.06

  

118.06 ± 3.21

  

Positive control

209.00 ± 2.00

  

1156.80 ± 17.43

  

13

209.00 ± 19.00

[7.68 ± 1.73]

273.00 ± 24.06

[−23.71 ± 2.17]

234.67 ± 13.27

[−4.58 ± 1.21]

976.00 ± 13.05

[26.66 ± 3.97]

1108.33 ± 2.00

[15.54 ± 0.61]

1243.67 ± 27.30

[4.17 ± 8.31]

14

333.00 ± 10.44

[−53.14 ± 9.51]

207.00 ± 13.00

[8.67 ± 1.81]

156.00 ± 15.17

[33.68 ± 3.21]

1242.00 ± 7.94

[4.31 ± 2.42]

1216.67 ± 2.11

[6.44 ± 6.73]

1250.00 ± 16.77

[3.64 ± 5.11]

15

238.67 ± 1.15

[−6.54 ± 2.47]

219.33 ± 5.50

[2.39 ± 1.02]

252.00 ± 17.69

[−13.40 ± 1.61]

1220.00 ± 10.26

[6.16 ± 3.13]

1236.00 ± 8.00

[4.82 ± 2.44]

1313.33 ± 26.51

[−1.68 ± 2.07]

16

175.33 ± 8.73

[24.36 ± 4.71]

187.67 ± 29.14

18.48 ± 5.72]

163.33 ± 9.29

[30.25 ± 5.01]

719.67 ± 5.04

[48.19 ± 8.21]

976.33 ± 13.57

[26.63 ± 3.18]

1209.67 ± 10.44

[7.03 ± 2.45]

17

179.00 ± 5.20

[22.40 ± 2.80]

177.00 ± 17.35

[23.38 ± 9.36]

216.33 ± 8.08

[4.25 ± 2.36]

576.00 ± 14.01

[60.26 ± 3.28]

723.33 ± 5.29

[47.88 ± 0.35]

836.67 ± 3.21

[38.36 ± 0.75]

18

220.00 ± 2.00

[2.29 ± 1.08]

224.00 ± 7.00

[0.33 ± 3.78]

210.67 ± 6.81

[7.19 ± 3.67]

700.00 ± 14.73

[49.84 ± 3.45]

886.67 ± 9.59

[34.16 ± 6.94]

880.00 ± 13.43

[34.72 ± 3.14]

Solvent blank

20.8 ± 4.18

  

103.00 ± 3.74

  

Positive control

224.67 ± 9.45

  

1293.33 ± 8.08

  

19

322.33 ± 49.52

[−51.77 ± 2.48]

195.50 ± 16.65

[12.33 ± 8.35]

182.67 ± 5.13

[19.06 ± 2.57]

1350.00 ± 30.00

[−35.35 ± 2.24]

1450.33 ± 10.27

[−46.23 ± 17.88]

1570.0 ± 26.46

[−59.28 ± 7.01]

20

144.33 ± 5.69

[38.28 ± 2.28]

159.00 ± 13.53

[30.69 ± 6.78]

226.00 ± 15.13

[−3.20 ± 7.59]

1056.67 ± 15.27

[−3.44 ± 1.68]

1653.33 ± 35.12

[−68.35 ± 7.02]

1396.67 ± 20.82

[−40.43 ± 4.32]

21

123.33 ± 16.04

[48.65 ± 8.04]

171.67 ± 10.02

[24.62 ± 5.02]

164.67 ± 15.01

[28.16 ± 7.52]

903.33 ± 5.77

[13.23 ± 4.51]

1112.67 ± 11.01

[−9.53 ± 10.40]

600.00 ± 34.64

[46.23 ± 3.016]

22

130.67 ± 26.01

[45.36 ± 15.46]

180.00 ± 4.00

[20.07 ± 2.37]

205.00 ± 10.44

[7.42 ± 6.21]

590.00 ± 5.77

[24.84 ± 0.59]

880.00 ± 26.46

[15.77 ± 4.03]

943.33 ± 11.55

[8.88 ± 5.62]

23

209.67 ± 4.51

[5.40 ± 2.68]

172.33 ± 10.69

[24.12 ± 6.36]

190.00 ± 8.72

[15.01 ± 5.18]

1017.67 ± 5.01

[0.80 ± 1.95]

1005.67 ± 10.69

[2.10 ± 4.91]

710.00 ± 10.16

[25.56 ± 5.60]

24

144.33 ± 21.13

[38.28 ± 12.56]

183.33 ± 16.17

[18.30 ± 9.61]

173.67 ± 13.65

[23.61 ± 8.12]

816.67 ± 22.66

[22.66 ± 2.12]

1011.33 ± 12.05

[1.49 ± 3.86]

870.00 ± 26.46

[16.86 ± 9..48]

Solvent blank

22.00 ± 4.61

  

105.67 ± 5.59

  

Positive control

219.67 ± 9.89

  

1025.60 ± 35.79

  

25

1607.67 ± 4.93

[27.89 ± 3.20]

174.67 ± 13.32

[20.24 ± 8.69]

186.33 ± 8.02

[13.68 ± 5.21]

856.67 ± 15.27

[22.76 ± 7.68]

1040.00 ± 10.00

[3.76 ± 6.13]

1180.00 ± 20.00

[−10.73 ± 0.63]

26

217.67 ± 14.29

[−3.28 ± 9.28]

186.33 ± 8.96

[13.68 ± 8.82]

190.00 ± 14.00

[11.49 ± 9.09]

870.00 ± 20.00

[21.38 ± 1.25]

1126.67 ± 30.55

[−5.22 ± 6.45]

1132.00 ± 25.53

[−5.77 ± 3.90]

27

194.67 ± 6.66

[9.30 ± 5.44]

202.33 ± 8.39

[4.92 ± 4.87]

175.33 ± 7.50

[19.69 ± 8.34]

1203.33 ± 26.17

[−13.16 ± 2.66]

1035.00 ± 5.00

[4.28 ± 3.74]

1057.33 ± 11.59

[1.97 ± 1.42]

28

223.33 ± 17.01

[−6.56 ± 1.13]

168.33 ± 14.84

[23.52 ± 9.89]

141.33 ± 13.58

[25.16 ± 9.09]

911.00 ± 20.05

[17.13 ± 2.75]

749.67 ± 11.93

[33.85 ± 9.43]

580.00 ± 17.32

[51.44 ± 7.54]

29

261.67 ± 13.05

[−54.16 ± 8.70]

165.67 ± 5.13

[−2.19 ± 3.42]

155.00 ± 19.97

[16.95 ± 3.32]

1031.67 ± 10.41

[4.63 ± 4.31]

760.00 ± 20.00

[32.78 ± 6.84]

746.67 ± 15.27

[34.16 ± 2.87]

30

200.00 ± 13.23

[6.01 ± 8.82]

179.50 ± 14.19

[17.23 ± 9.46]

190.67 ± 17.47

[11.49 ± 1.64]

583.33 ± 20.82

[51.09 ± 7.23]

476.67 ± 15.27

[62.14 ± 0.66]

615.00 ± 35.00

[47.81 ± 1.16]

31

71.00 ± 7.00

[76.58 ± 4.67]

201.67 ± 9.45

[5.47 ± 6.30]

171.33 ± 19.65

[21.88 ± 13.1]

118.00 ± 15.62

[99.32 ± 2.95]

160.00 ± 10.00

[94.96 ± 7.25]

746.67 ± 45.09

[34.16 ± 5.59]

Solvent blank

28.2 ± 6.57

  

111.40 ± 11.13

  

Positive control

211.67 ± 7.57

  

1076.33 ± 26.95

  
  1. The results are expressed as mean number of revertants/plate (± SD) percentage antimutagenicity [in squared brackets]