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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Douchi (fermented Glycine max Merr.) alleviates atopic dermatitis-like skin lesions in NC/Nga mice by regulation of PKC and IL-4

Fig. 4

Regulating effects of Douchi on cytokines secretion of mast cell. In Luna’s staining, more granulated mast cells (arrows indicate purple) were observed in the dermis of DT than in that of AD. Decreased numbers of substance P-positively reacted cells (arrow indicates dark brown) were observed in the DT compared with the AD. In MMP-9 immunohistochemistry results, MMP-9-positively reacted cells (arrow indicates dark brown in dermal macrophage) decreased in the DT compared to the AD. In M/T results, collagen fibers (bright blue) decreased in AD compared with DT. Arrows (↕) indicate hyperplasia of the epithelium. Bar size: 100 μm. *: p < 0.01 compared with AD, #: p < 0.01 compared with Ctrl. Abbreviations; M/T : Masson’s trichrome staining

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