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Table 2 Effect of carob pods extract (CPE) administration on worm burden, liver tissue eggs load and granuloma size of S. mansoni infected mice

From: Ceratonia siliqua pod extract ameliorates Schistosoma mansoni-induced liver fibrosis and oxidative stress

Groups Mean number of worms ± SEM Reduction on worm burden (%) Ova count in liver ± SEM Reduction on ova count (%) Granuloma size (μm2)
Vehicle control 15.3 ± 1.37 - 11.4 ± 1.08 - 968500 ± 1364
PZQ (500 mg/kg bwt) 4.7 ± 0.52a 69.5a 2.3 ± 0.71a 79.8a 915400 ± 1519
CPE (300 mg/kg bwt) 9.3 ± 1.36a 39.0a 5.7 ± 0.34a 50.0a 882200 ± 757a
CPE (600 mg/kg bwt) 7.0 ± 0.89a 54.2a 3.1 ± 0.28a 72.8a 808900 ± 361a
  1. Values are means ± SEM (n = 5). a p < 0.05, significant change with respect to the Vehicle control
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