Fig. 7From: Chalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cellsEffects of chalepin at different concentrations on nuclear morphological changes of A549 cell line at 48 h and 72 h incubation. After the incubation period, the cells were stained with Hoechst 33342 and PI and were examined with a fluorescent microscope under magnification of 400x to observe the chromatin condensation, nuclear fragmentation and cell shrinkageBack to article page