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Table 2 Post-infection AA5, 10, 20 oral administration influence on food intake changes compared to controls

From: Asiatic acid influences parasitaemia reduction and ameliorates malaria anaemia in P. berghei infected Sprague–Dawley male rats

Parameter Post-infection treatment Pre-patent (D 3) Patent/Treatment (D7–12) Post-treatment (D13- 21)
Food intake (g/100 g) NIC 12.3 ± 2.3 13 ± 9.0 13.4 ± 1.6
IC 11.5 ± 1.9 6.7 ± 1.3 N/A
30CHQ 12.3 ± 1.8 7.8 ± 2.0 8.6 ± 1.7
5 AA 12.9 ± 1.3 9.8 ± 1.3*# 9.7 ± 1.5*#
10 AA 12.3 ± 1.8 12.9 ± 2*# 13.2 ± 0.72#
20 AA 12.7 ± 1.6 9.2 ± 1.6α* 10.3 ± 1.2#
  1. NIC is non-infected treated control, IC is infected non-treated control and CHQ is chloroquine control (30 mg/kg). Values are presented as means ± SEM, (n = 6 in each group). α,*,#p < 0.05 by comparison with NIC, IC, 30CHQ groups, respectively. NIC non infected treated control, IC infected control, CHQ chloroquine, AA asiatic acid