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Table 1 Inhibitory effect of the crude extract and fractions of Zea mays L. on protein tyrosine phosphatase 1β

From: Optimization of extraction parameters of PTP1β (protein tyrosine phosphatase 1β), inhibitory polyphenols, and anthocyanins from Zea mays L. using response surface methodology (RSM)

Extract and fractions Concentration (μg/mL) Inhibition (%) IC50b (μg/mL)
Suramina 12.97 61.88  
6.49 40.62 7.51
3.21 10.69  
EtOH ext. 100 43.99 -
n-Hex fr. 100 25.54 -
CH2Cl2 fr. 100 28.12 -
EtOAc fr. 100 83.88  
50 57.23 26.12
10 44.77  
n-BuOH fr. 100 70.89  
50 45.09 58.20
10 26.87 -
Water fr. 100 47.50 -
  1. aSuramin was used as positive control
  2. bThe IC50 value was defined as the half-maximal inhibitory concentration and mean of 3 duplicate analyses of each sample