Table 1 Anti-edematogenic effect of rutin, chlorogenic acid and the aqueous extract from the fruits of Hancornia speciosa in xylene-induced ear edema model
Groups (treatment i.p.) | Dose (mg/kg) | Difference (mg) | Inhibition (%) |
|---|---|---|---|
Saline | ---- | 32.450 ± 2.603 | |
Dexamethasone | 0.5 | 6.600 ± 2.448*** | 79.66 |
Aqueous extract | 40 | 7.020 ± 3.820*** | 78.36 |
Aqueous extract | 50 | 6.140 ± 2.385*** | 81.07 |
Aqueous extract | 60 | 8.700 ± 2.719*** | 73.18 |
Rutin | 2.5 | 7.480 ± 2.221*** | 76.94 |
Rutin | 5 | 5.420 ± 2.328*** | 83.29 |
Rutin | 10 | 0.720 ± 1.253*** | 97.78 |
Chlorogenic acid | 10 | 4.600 ± 2.795*** | 85.82 |
Chlorogenic acid | 12.5 | 5.460 ± 2.579*** | 83.17 |
Chlorogenic acid | 15 | 6.540 ± 3.917*** | 79.84 |