Skip to main content

Table 1 Anti-edematogenic effect of rutin, chlorogenic acid and the aqueous extract from the fruits of Hancornia speciosa in xylene-induced ear edema model

From: Anti-inflammatory activity of aqueous extract and bioactive compounds identified from the fruits of Hancornia speciosa Gomes (Apocynaceae)

Groups (treatment i.p.) Dose (mg/kg) Difference (mg) Inhibition (%)
Saline ---- 32.450 ± 2.603  
Dexamethasone 0.5 6.600 ± 2.448*** 79.66
Aqueous extract 40 7.020 ± 3.820*** 78.36
Aqueous extract 50 6.140 ± 2.385*** 81.07
Aqueous extract 60 8.700 ± 2.719*** 73.18
Rutin 2.5 7.480 ± 2.221*** 76.94
Rutin 5 5.420 ± 2.328*** 83.29
Rutin 10 0.720 ± 1.253*** 97.78
Chlorogenic acid 10 4.600 ± 2.795*** 85.82
Chlorogenic acid 12.5 5.460 ± 2.579*** 83.17
Chlorogenic acid 15 6.540 ± 3.917*** 79.84
  1. Values are mean ± standard deviation (S.D.), n = 5, ***p < 0.001, tested-group compared to saline-treated group