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Table 3 Effect of crude hydromethanolic root extract of root of Indigofera spicata on intestinal motility using charcoal as a marker in mice

From: Antidiarrheal activity of crude methanolic root extract of Idigofera spicata Forssk.(Fabaceae)

Group Total intestinal length (cm) Distance travelled by charcoal (cm) % Intestinal transit of charcoal % Inhibition
NS 55.67 ± 2.16 49.67 ± 2.06†† 89.23 ± 1.26†† 0.00
Atropine 57.83 ± 1.14 16.33 ± 1.78 28.15 ± 2.90 68.45
100 mg/kg IS 54.17 ± 2.15 47.67 ± 1.45†† 88.21 ± 1.62†† 1.14
200 mg/kg IS 53.17 ± 1.54 45.17 ± 1.89†† 85.13 ± 3.47†† 4.59
400 mg/kg IS 58.33 ± 1.36 46.17 ± 1.94†† 79.20 ± 3.11†† 11.24
  1. Values are mean ± S.E. (n = 6), †† refers p < 0.001 compared to the positive control