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Table 3 The changes in ALAT, ASAT, ALP and Bilirubin levels after oral therapy with SPW1

From: Glycoside rich fraction from Spondias pinnata bark ameliorate iron overload induced oxidative stress and hepatic damage in Swiss albino mice

Treatment ALAT ASAT ALP Bilirubin
Unit/L % change Unit/L % change Unit/L % change mg/dl % change
B 14.42 ± 1.91   62.46 ± 6.32   84.62 ± 3.48   1.58 ± 0.10  
C 64.60 ± 0.73 X3 347.88 234.91 ± 8.30 X3 276.13 252.63 ± 4.92 X3 198.56 3.15 ± 0.18 X3 99.67
S50 36.19 ± 1.16 X3Y3 150.91 170.49 ± 12.54 X3Y3 172.97 181.71 ± 6.18 X3Y3 114.74 2.42 ± 0.25 X2Y2 53.43
S100 27.47 ± 1.55 X3Y3 90.45 137.29 ± 17.82 X3Y3 119.82 149.48 ± 7.02 X3Y3 76.66 2.18 ± 0.12 X3Y3 38.41
S200 20.11 ± 0.16 X2Y3 39.41 97.62 ± 8.16 X3Y3 56.31 125.08 ± 5.93 X3Y3 47.81 1.99 ± 0.13 X3Y3 26.22
D 19.85 ± 0.79 X3Y3 37.59 88.06 ± 10.37 X2Y3 40.99 114.97 ± 6.13 X3Y3 35.87 1.72 ± 0.14 X1Y3 8.92
  1. Mouse groups (B; C; S50, S100, S200, D) were treated as described in ‘Experimental design’ section. Values are mean ± SD (n = 6). X1: p < 0.05, X2: p < 0.01 and X3: p < 0.001 significant difference from B group. Y1: p < 0.05, Y2: p < 0.01 and Y3: p < 0.001 significant difference from C group