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Table 5 Cytotoxic effect of A. hydaspica methanol extract and its derived fractions on MDA-MB 361, HCC-38 and Vero cells of green monkey after 48 h of treatment

From: Evaluation of antioxidant, anti-hemolytic and anticancer activity of various solvent extracts of Acacia hydaspica R. Parker aerial parts

Extract/Fraction MDA361 cell line SI HCC38 cell line SI Vero cell line
  IC50 (μg/ml) IC50V/IC50M IC50 (μg/ml) IC50V/IC50H IC50 (μg/ml)
AHM 46.9 ± 1.31* 5.42 75.9 ± 1.32* 3.34 254 ± 1.81
AHE 29.9 ± 0.91* 9.83 39.5 ± 0.87* 7.44 294 ± 1.55
AHB 37.1 ± 1.01* 6.97 56.1 ± 0.93* 4.60 258 ± 1.68
  1. Each value expressed as mean ± SEM (n = 3). Selectivity index (SI) >3 is considered to be highly selective, * shows significance at p <0.001 as compared to Vero cells. M represents MDA-MB-361; V represents Vero and H represents HCC38 cell lines. (One way ANOVA followed by Tukey’s multiple comparison test)