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Table 2 Determination of EC50 and CC50 of Cortex phellodendri in RAW264.7, HEK293T and HeLa cells

From: Inhibitory effects of an aqueous extract from Cortex Phellodendri on the growth and replication of broad-spectrum of viruses in vitro and in vivo

Cell Ec50 ± S.D.b(μg/ml) CC50 ± S.D.c(μg/ml)
PR8-GFP VSV-GFP NDV-GFP H3-GFP HSV-GFP EV-71
Raw264.7 0.89 ± 0.09 0.71 ± 0.15 0.57 ± 0.13 - - - 7.31 ± 0.12
HEK293T - 0.63 ± 0.06 - - 0.83 ± 0.07 - 6.36 ± 0.06
HeLa - - - 0.75 ± 0.12 - 0.39 ± 0.07a 8.06 ± 0.04
  1. aEffective concentration for 50 % reduction in CPE
  2. bEffective concentration for 50 % reduction in GFP expression
  3. cCytotoxic concentration causing 50 % cell death. The results are a mean of three independent experiments