Fig. 1From: ZiBu PiYin recipe prevents diabetes-associated cognitive decline in rats: possible involvement of ameliorating mitochondrial dysfunction, insulin resistance pathway and histopathological changesDesign of the animal study. The control group was fed with standard diet during the whole study. The two diabetic groups received high-fat diet until drug intervention (ZBPYR). In week 4 of the timeline, the two diabetic groups received STZ, while the control group was administered vehicle citrate buffer. At 72Â h, and 7, 12 and 16Â days after STZ, RBG, FSI, OGTT and ITT were tested. From 7Â weeks after the STZ injection, ZBPYR was administered to the ZBPYR group daily for 7Â weeks. The Control and Model groups received physiological saline. The Morris water maze test was performed for 6Â days before animals sacrificedBack to article page