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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy

Fig. 2

Enrichment of BCSCs in MCF7/C6 cells. a Flow cytometry analysis for different stem-cell surface markers in MCF7 and MCF7/C6 cells (left); b Increased CD44 expression in MCF7/C6 cells comparing to parental MCF7 cells. Top: flow cytometry analysis of CD44 expression; Bottom left: diagram showing the percentages of cell populations with CD44 expression; Bottom right: Western blot analysis for CD44 protein expression. Data represent the average from at least three independent experiments. c Diagram (right) showing the changes of the cell fractions with corresponding positive stem cell markers. d Tumorogenesis of MCF7/C6 cells verses MCF7 cells. Top: images for collected tumors from Tumor initiating test; bottom: diagram showing the average of tumor volumes. *Indicates statistical significance (p < 0.05)

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