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Table 2 Effect of the drug treatments on the relative organ weight, disease activity index, macroscopic scoring and serum biochemical parameters in indomethacin induced CD in rats

From: Emu oil offers protection in Crohn’s disease model in rats

  Macroscopic scoring ROW DAI (g/cm)
Group day 6 day 9 day 6 day 9 day 6 day 9
Control - - 0.033a ± 0.008 0.033a ± 0.001 0.063a ± 0.0013 0.061a ± 0.0016
Indomethacin 2.20d ± 0.20 1.43b ± 0.20 0.054b ± 0.002 0.056d ± 0.001 0.092b ± 0.003 0.082b ± 0.0017
Sulfasalazine 2.00cd ± 0.32 0.71a ± 0.36 0.037a ± 0.003 0.041bc ± 0.001 0.0681a ± 0.0013 0.063a ± 0.0027
Aloe vera 1.60bcd ± 0.25 0.50a ± 0.22 0.048ab ± 0.0006 0.049c ± 0.0021 0.067ab ± 0.0047 0.064a ± 0.0016
Emu oil 1.00abc ± 0.32 Nil 0.045ab ± 0.004 0.039ab ± 0.003 0.067a ± 0.0033 0.064a ± 0.0032
Aloe vera and emu oil combination 0.60a ± 0.25 Nil 0.041ab ± 0.0024 0.042bc ± 0.001 0.077ab ± 0.0062 0.063a ± 0.0045
  Day 6 Day 9
Group Cholesterol (mg/dL) ALP (U/L) Cholesterol (mg/dL) ALP (U/L)
Control 63.24a ± 2.14 103.23a ± 1.01 68.45a ± 6.58 106.77a ± 12.37
Indomethacin 61.74a ± 3.045 272.28c ± 25.18 49.80a ± 5.42 274.33c ± 11.74
Sulfasalazine 50.69a ± 9.23 182.67b ± 23.76 52.36a ± 1.53 224.40bc ± 17.81
Aloe vera 61.28a ± 9.27 182.66b ± 8.71 62.38a ± 4.22 169.05abc ± 41.01
Emu oil 57.75a ± 7.30 138.54ab ± 8.12 64.35a ± 4.65 153.50ab ± 21.45
Aloe vera and emu oil combination 56.44a ± 9.48 177.32b ± 20.09 54.98a ± 8.44 154.60ab ± 29.65
  1. All the values were expressed as Mean ± S.E. (n = 6) and means bearing different superscripts in a column differ significantly