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Table 1 Effect of GXD on hemodynamic parameters and cardiac function induced by coronary artery ligation

From: Gualou Xiebai decoction inhibits cardiac dysfunction and inflammation in cardiac fibrosis rats

  sham MI GXDL GXDH
HR(beats/min) 359.6 ± 42.3 259.8 ± 29.5 306.0 ± 55.4* 333.7 ± 57.2**
SBP(mmHg) 107.1 ± 10.1 82.9 ± 7.7 88.4 ± 7.3 99.1 ± 10.2**
DBP(mmHg) 69.93 ± 10.47 56.48 ± 8.07 62.59 ± 5.26* 67.26 ± 11.65*
+LV dp/dtmax(mmHg/s) 5287.03 ± 1247.53 3312.07 ± 859.48 4062.42 ± 623.19* 4752.61 ± 930.10**
-LV dp/dtmin(mmHg/s) 4099.12 ± 759.61 3005.07 ± 517.25 3357.75 ± 774.67 3822.46 ± 905.39*
LVSP(mmHg) 120.99 ± 10.15 88.94 ± 6.86 95.70 ± 7.57* 105.24 ± 9.85**
LVEDP(mmHg) −4.57 ± 1.71 5.72 ± 1.44 2.69 ± 0.88** −0.98 ± 1.70**
  1. Values are expressed as the mean ± S.D. (n = 8 for Sham group and n = 12 for other groups). HR heart rate, SBP systolic blood pressure, DBP diastolic pressure, ±LV dp/dt max the maximal rates of increase and decrease of left ventricle pressure development, LVSP left ventricular systolic pressure, LVEDP left ventrilcel end dilated pressure. P < 0.01 vs sham group; *P < 0.05, **P < 0.01 vs MI group