Fig. 2

Effects of MNZQ on hot plate analgesic test in mice. The time between the placement of mouse and its shaking or licking of the hind paws on a hot plate for 30, 60, 90, and 120 min after administration was recorded as reaction time. Vehicle control mice were administered with distilled water, and ASA (100 mg/kg) was used as the positive control. Results are expressed as the mean ± SEM (n = 8) of the reaction time in seconds. *p < 0.05, **p < 0.01, ***p < 0.001 were considered significant when compared at the same time with the vehicle control (distilled water) after administration