Table 2 Antibacterial activity of ent-copalic acid against multiresistant Gram-positive and Gram-negative bacteria
Minimum Inhibitory Concentration - µg mL−1 | ||
|---|---|---|
Multiresistant Microorganisms | Copalic acid (OC-2) | Positive Control |
S. epidermidis (ATCC 14490) | 50.0 | 1.5 |
S. epidermidis (clinical isolate) | 15.6 | 1.5 |
S. capitis (ATCC 27840) | 50.0 | 0.7 |
S. capitis (clinical isolate) | 31.25 | 0.7 |
S. aureus (WB81-USA 400) | 25.0 | 0.7 |
S. aureus (W7749-USA 200) | 25.0 | 0.7 |
S. aureus (ATCC 29213) | 25.0 | 0.7 |
S. aureus (surgical wound) | 15.6 | 1.5 |
S. aureus (catheter) | a | 1.5 |
E. faecalis (ATCC 19433) | 25.0 | 1.5 |
E. faecalis (clinical isolate) | 15.6 | 5.9 |
E. faecium (ATCC 19434) | 50.0 | 1.5 |
E. faecium (hospital outbreak) | 50.0 | 5.9 |
S. haemolyticus (ATCC 29970) | 100.0 | 1.5 |
S. haemolyticus (clinical isolate) | 15.6 | 1.5 |
S. pneumoniae (clinical isolate) | 31.25 | 2.9 |
P. aeruginosa (clinical isolate) | a | 5.9 |
A. calcoaceticus (clinical isolate) | a | 0.4 |
E. coli (clinical isolate) | a | 5.9 |
K. pneumoniae (clinical isolate) | a | 2.9 |