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Table 1 Effects of TQF (10 mg/kg, 30 mg/kg and 100 mg/kg) on ‘promotion’ stage of DMBA/TPA-induced mouse skin tumorigenesis after 20 weeks

From: Low dose triterpene-quinone fraction from Ardisia crispa root precludes chemical-induced mouse skin tumor promotion

Group Body weight (g) Tumor Incidence (%) Tumor burden Tumor volume (mm3)  
  Initial Final    
I 20.5 ± 0.43 32.4 ± 0.93 - - -
II 23.3 ± 0.54 35.4 ± 1.01 60a 2.00 ± 0.37a 7.62 ± 3.51a
III 23.6 ± 0.64 32.3 ± 0.56 25b 1.50 ± 0.50a 4.59 ± 3.58a,b
IV 20.7 ± 0.50 32.8 ± 0.97 33.3c 1.00 ± 0.00b 1.48 ± 0.37b
V 21.8 ± 0.49 33.3 ± 1.09 77.8a 2.29 ± 0.52a 9.16 ± 3.21c
VI 21.7 ± 0.30 31.6 ± 0.70 100d 7.30 ± 1.07c 13.67 ± 5.29d
VII 22.4 ± 0.81 33.2 ± 1.98 - - -
VIII 21.2 ± 0.73 32.8 ± 0.49 - - -
IX 20 ± 0.48 33.8 ± 1.18 - - -
  1. Values expressed as mean ± S.E.M. (group I-VI, n = 10; group VII-IX, n = 5)
  2. Values with different superscript letters(a, b,c, d) within the same column are statistically different (P < 0.05)
  3. Group: I (vehicle control); II (carcinogen control); III (reference group, 10 mg/kg curcumin); IV (10 mg/kg TQF); V (30 mg/kg TQF); VI (100 mg/kg TQF); VII (treatment control, 10 mg/kg TQF); VIII (treatment control, 30 mg/kg TQF); IX (treatment control, 100 mg/kg TQF)