Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus

Table 1 Effects of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus on healing in acetic acid-induced gastric lesion

Gastric lesion models	Treatment (p.o.)	Dose (mg/kg)	ALU (mm²)	Inhibition (%)
Acetic acid	Saline	-	75 ± 8,6	-
	Cimetidine	100	22 ± 2,5**	71
	Sa-FRF	100	42 ± 1,6*	44
	Sa-FDF	100	65 ± 7,0	13
	Sb-FRF	100	49 ± 4,3*	35
	Sb-FDF	100	67 ± 25	11

ANOVA followed by Dunnett’s test.*p < 0.05, **p < 0.01. Data are presented as mean ± S.D (n = 5-7)

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