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Table 1 Effect of IFA on the formation of non-fluorescent Nε-CML and carbonyl content in BSA incubated with MG at week 2

From: Isoferulic acid prevents methylglyoxal-induced protein glycation and DNA damage by free radical scavenging activity

Experiments

Nε-CML

Carbonyl content

 

(ng/mL)

(nmol/mg protain)

BSA

2.97 ± 0.21

0.14 ± 0.02

BSA / MG

5.75 ± 0.50a

1.89 ± 0.11a

BSA / MG / IFA (1.25 mM)

4.03 ± 0.44b

1.34 ± 0.40b

BSA / MG / IFA (2.5 mM)

3.93 ± 0.27b

0.97 ± 0.08b

BSA / MG / IFA (5 mM)

3.37 ± 0.44b

0.90 ± 0.11b

BSA / MG / AG (1.25 mM)

3.62 ± 0.40b

0.41 ± 0.08b

  1. The results are presented as mean ± SEM (n = 3). a p <0.05 when compared to BSA; b p <0.05 when compared to BSA/MG