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Table 4 Antidepressant effects of methanolic extract of B. monniera in measurement of locomotor activity test

From: Antidepressant-like effects of methanolic extract of Bacopa monniera in mice

Treatment Doses (mg/kg) Locomotion Rearing Defecation
Deionized water 0.1 mL/mice 107.80 ± 2.92 23.00 ± 2.02 1.00 ± 0.31
Imipramine hydrochloride 30 206.60 ± 3.01* 36.60 ± 1.60* 3.20 ± 0.37*
MEBM 50 91.40 ± 4.25* 27.80 ± 2.13 1.60 ± 0.40
MEBM 100 121.40 ± 4.46 37.20 ± 1.93* 3.20 ± 0.37*
MEBM 200 153.80 ± 3.61* 47.20 ± 2.03* 4.20 ± 0.37*
  1. Values are presented as mean ± SEM (n = 5). MEBM = Methanolic extract of B.monniera
  2. *p < 0.001 compared with the control group (Dunnett’s test)