Antidepressant-like effects of methanolic extract of Bacopa monniera in mice

Table 4 Antidepressant effects of methanolic extract of B. monniera in measurement of locomotor activity test

Treatment	Doses (mg/kg)	Locomotion	Rearing	Defecation
Deionized water	0.1 mL/mice	107.80 ± 2.92	23.00 ± 2.02	1.00 ± 0.31
Imipramine hydrochloride	30	206.60 ± 3.01*	36.60 ± 1.60*	3.20 ± 0.37*
MEBM	50	91.40 ± 4.25*	27.80 ± 2.13	1.60 ± 0.40
MEBM	100	121.40 ± 4.46	37.20 ± 1.93*	3.20 ± 0.37*
MEBM	200	153.80 ± 3.61*	47.20 ± 2.03*	4.20 ± 0.37*

Values are presented as mean ± SEM (n = 5). MEBM = Methanolic extract of B.monniera
*p < 0.001 compared with the control group (Dunnett’s test)

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