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Table 1 Antimycobacterial activity of terpenes and phenylpropanes against M. tuberculosis and M. bovis

From: Quantitative structure-activity relationship of molecules constituent of different essential oils with antimycobacterial activity against Mycobacterium tuberculosis and Mycobacterium bovis

Compounds   Antimycobacterial activity (μg/mL)
  M. tuberculosis M. bovis
MIC MIC
1 Cinnamic Acid 8.16 ± 3.32FG 7.29 ± 4.73DE
2 Camphor 41.66 ± 14.43CD 50.00 ± 0.00B
3 p-Anisaldehyde 4.16 ± 1.81FG 10.41 ± 3.61DE
4 β-pinene 10.41 ± 3.61CDE 41.66 ± 14.43CDE
5 3-Carene 16.66 ± 7.22CDEF 33.33 ± 14.43CDE
6 p-Cymene 91.66 ± 14.43 A 91.66 ± 14.43 A
7 β-Caryophyllene 100.00 ± 0.00 A 100.00 ± 0.00 A
8 Carvacrol 2.02 ± 0.88FG 5.20 ± 1.81DE
9 (+) Carvone 20.83 ± 7.22CDE 41.33 ± 15.01BCDE
10 Cinnamaldehyde 3.12 ± 0.00EFG 12.50 ± 0.00DE
11 β-Citronellol 6.25 ± 0.00FG 10.41 ± 3.61DE
12 Cuminaldehyde 10.41 ± 3.61DEFG 20.83 ± 7.22CDE
13 Estragole 20.83 ± 7.22DEFG 25.00 ± 0.00BCDE
14 Eucalyptol 41.66 ± 14.43CDE 41.66 ± 14.43B
15 Eugenol 25.00 ± 0.00DEFG 20.83 ± 7.22BCD
16 Geraniol 12.50 ± 0.00EFG 12.50 ± 0.00 CDE
17 (+) Limonene 25.00 ± 0.00CDE 41.66 ± 14.43BCD
18 Linalool 33.33 ± 14.43CDE 41.66 ± 14.43BC
19 Menthol 41.66 ± 14.43 AB 83.33 ± 14.43B
20 Myrcene 25.00 ± 0.00CDEF 33.33 ± 14.43BCD
21 Sabinene 33.33 ± 14.43DEFG 25.00 ± 0.00BC
22 t-Anethole 20.83 ± 7.22BC 58.33 ± 14.43BCDE
23 α-Terpinene 10.41 ± 3.61DEFG 20.83 ± 7.22CDE
24 Terpinolene 8.33 ± 3.61CDEF 33.33 ± 14.43DE
25 Thymol 0.78 ± 0.01G 2.02 ± 0.88E
TX Isoniazid 0.26 ± 0.01G 0.16 ± 0.3E
TX Rifampicin 0.60 ± 0.14G 0.50 ± 0.01E
  1. Values are the average and standard deviation of triplicate assays. Superscripts correspond to clusters by similarity analysis done by Tukey mean analysis