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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Study of the protective effect on intestinal mucosa of the hydrosoluble fiber Plantago ovata husk

Fig. 1

Light micrographs of rabbit duodenal mucosa showing the effect of Plantago ovata husk on aspirin-induced lesions. a and b Normal mucosa in control animals. d After 14-day aspirin treatment, epithelium disorganization and vacuolization was observed, with losses of content cell and nuclei (arrows), (e) also increasing the presence of caliciform cells in epithelium. In rabbits treated with fiber and aspirin for 14 days (c and f) Plantago ovata protected against aspirin-induced lesions, maintaining enterocyte integrity and keeping the number of caliciform cells close to control values (arrows). g After 28-day aspirin administration, villi are flattened and showed important erosions with 28-day treatment, and (h) the number of caliciform cells increased significantly, probably to augment mucin secretion. i Pretreatment with Plantago ovata husk for 28 days protected against aspirin-induced lesions, maintaining as well epithelium integrity. Hematoxyline and eosin staining: a, c and d, 40X, scale bar 20 μm; g, 4X, scale bar 100 μm. Periodic acid-Schiff (PAS) staining: b and f, 20X, scale bar 40 μm; i, 40X, scale bar 20 μm; h 10X, scale bar 50 μm. Alcian blue-PAS staining: e 40X, scale bar 20 μm

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