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Table 2 Subacute effect of carob pods aqueous extract (CPAE), famotidine (FAM) and ascorbic acid (AA) on macroscopic quantitative changes induced by EtOH in rats: ulcer mucus volume, ulcer area and percentage protection. Animals were pre-treated with various doses of CPAE (500, 1000 and 2000 mg/kg, b.w., p.o.), FAM (10 mg/kg, b.w., p.o.) or bi-distilled water, challenged with a single oral administration of EtOH (4 g/kg, b.w., p.o.) or NaCl 9‰ for two hours

From: Gastroprotective effect of carob (Ceratonia siliqua L.) against ethanol-induced oxidative stress in rat

Group Mucus volume (ml) Ulcer index (mm2) Protection percentage (%)
Control 4.3 ± 0.20 ---- ----
EtOH 1.9 ± 0.3* 86.2 ± 2.6* 00
EtOH + CPAE-500 2.9 ± 0 67.0 ± 3.6# 23.4
EtOH + CPAE-1000 3.4 ± 0.2# 16.6 ± 1.4# 79.8
EtOH + CPAE-2000 3.9 ± 0.3# 06.4 ± 0.9# 92.2
EtOH + FAM 3.8 ± 0.2# 26.2 ± 3.3# 68.1
  1. *: p < 0.05 compared to control group and #: p < 0.05 compared to EtOH group