Antimicrobial and cytotoxicity properties of the crude extracts and fractions of Premna resinosa (Hochst.) Schauer (Compositae): Kenyan traditional medicinal plant

Table 6 Antimicrobial activity for P. resinosa fractions

Fractions	Diameter of zone of inhibition in mm
	Microorganism
	Gram positive		Gram negative					Fungi
	SA	MRSA	PA	EC	KP	SH	ST	CA	CR
PE	18 ± 0.6	NT	0	11.3 ± 0.3	0	0	0	10.3 ± 0.3	NT
DCM	19.3 ± 0.3	10.6 ± 0.6	0	10.3 ± 0.3	0	9.7 ± 0.7	0	9.3 ± 0.3	0
EA	22.3 ± 0.3	0	0	0	NT	11.7 ± 0.3	0	6.3 ± 0.3	7.3 ± 0.3
MOH	19.0 ± 0.6	10.7 ± 0.9	0	11.7 ± 0.3	7.3 ± 0.3	12.3 ± 0.3	7.0 ± 0.6	10.0 ± 0.6	NT
PC	33.7 ± 0.3	24.3 ± 0.3	23.7 ± 0.6	17 ± 0.6	15.7 ± 0.3	19.7 ± 0.6	21.3 ± 0.3	16.3 ± 0.3	20.3 ± 0.3
NC	0	0	0	0	0	0	0	0	0

PE Petro ether fraction at 5 μg/disc, DCM Dichloromethane fraction at 5 μg/disc, EA Ethyl acetate fraction at 2.5 μg/disc, MOH Methanol fraction at 5 μg/disc, PA P. aerogenosa, EC E. coli, SA S. aureus, KP K. pneumoniae, MRSA Methicillin Resistant S. aureus, SH Shigella, ST S. typhi, CA C. albicans, CR Cryptococcus, PC Positive control (Oxacillin 10 μg/disc and Gentamycin 10 μg/disc for Gram positive and Gram negative bacteria respectively. Nystatin 100 μg/disc for fungi), NC Negative control (Discs loaded with 10 μl of DMSO), n = 3, values Mean ± SEM

ISSN: 2662-7671