Groups | NIC | IC | PZQ | CuF100 | CuF200 | CuF400 |
---|---|---|---|---|---|---|
Number of animals (n) | 5 | 6 | 6 | 6 | 6 | 6 |
ALT (U/mL) | 266.28 ± 9.90 | 746.07 ± 59.86 | 391.66 ± 31.85 | 408.49 ± 36.27 | 420.52 ± 26.68 | 481.76 ± 47.09 |
p | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | |
% change | +180.18 | −47.50 | −45.25 | −43.63 | −35.43 | |
AST (U/m) | 167.84 ± 10.55 | 234.23 ± 14.58 | 168.13 ± 13.41 | 234.52 ± 23.74 | 248.24 ± 20.11 | 261.75 ± 16.25 |
p | n.s | n.s | n.s | n.s | n.s | |
% change | +39.55 | −28.22 | +0.12 | +5.98 | +11.75 | |
ALP (U/L) | 19.02 ± 2.87 | 8.04 ± 2.88 | 20.68 ± 3.24 | 13.10 ± 2.90 | 18.38 ± 2.86 | 20.33 ± 4.07 |
p | n.s | n.s | n.s | n.s | n.s | |
% change | −57.73 | +157.21 | +62.93 | +128.61 | +152.86 | |
Total proteins (mg/mL) | 4.43 ± 0.22 | 3.17 ± 0.29 | 4.73 ± 0.15 | 4.88 ± 0.18 | 5.39 ± 0.18 | 4.59 ± 0.16 |
p | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | |
% change | −28.44 | +49.21 | +53.94 | +70.03 | +44.79 | |
Total bilirubin (μmol/L) | 19.34 ± 1.71 | 23.15 ± 1.80 | 15.32 ± 1.76 | 16.87 ± 3.78 | 20.84 ± 1.50 | 25.59 ± 3.88 |
p | n.s | n.s | n.s | n.s | n.s | |
% change | +19.70 | −33.82 | −27.13 | −9.98 | +10.54 |