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Table 1 Effect of XKA on serum lipid profile in diabetic KKAy mice

From: Evaluating the antidiabetic effects of Chinese herbal medicine: Xiao-Ke-An in 3T3-L1 cells and KKAy mice using both conventional and holistic omics approaches

  C57BL/6J KKAy KKAy + XKA-H KKAy + XKA-L KKAy + MET
TG (mmol/L) 1.29 ± 0.17 2.03 ± 0.85# 1.41 ± 0.59* 1.65 ± 0.33 1.64 ± 0.56
TC (mmol/L) 2.33 ± 0.21 4.61 ± 1.01## 4.92 ± 1.65 4.44 ± 0.83 4.85 ± 0.97
HDL-c (mmol/L) 1.42 ± 0.16 2.75 ± 0.60## 3.42 ± 1.42 2.94 ± 0.70 3.21 ± 0.75
LDL-c (mmol/L) 0.408 ± 0.075 0.565 ± 0.121# 0.617 ± 0.169 0.513 ± 0.111 0.565 ± 0.087
TC/HDL-c 1.64 ± 0.07 1.68 ± 0.13 1.48 ± 0.17** 1.53 ± 0.14* 1.53 ± 0.15*
Atherogenic index 0.639 ± 0.066 0.685 ± 0.127 0.483 ± 0.167** 0.530 ± 0.145* 0.533 ± 0.146*
  1. All values are means ± SD (n = 10–11)
  2. #p < 0.05 vs. C57BL/6J mice
  3. ##p < 0.01 vs. C57BL/6J mice
  4. *p < 0.05 vs. KKAy mice
  5. **p < 0.01 vs. KKAy mice