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Table 1 Effect of XKA on serum lipid profile in diabetic KKAy mice

From: Evaluating the antidiabetic effects of Chinese herbal medicine: Xiao-Ke-An in 3T3-L1 cells and KKAy mice using both conventional and holistic omics approaches

 

C57BL/6J

KKAy

KKAy + XKA-H

KKAy + XKA-L

KKAy + MET

TG (mmol/L)

1.29 ± 0.17

2.03 ± 0.85#

1.41 ± 0.59*

1.65 ± 0.33

1.64 ± 0.56

TC (mmol/L)

2.33 ± 0.21

4.61 ± 1.01##

4.92 ± 1.65

4.44 ± 0.83

4.85 ± 0.97

HDL-c (mmol/L)

1.42 ± 0.16

2.75 ± 0.60##

3.42 ± 1.42

2.94 ± 0.70

3.21 ± 0.75

LDL-c (mmol/L)

0.408 ± 0.075

0.565 ± 0.121#

0.617 ± 0.169

0.513 ± 0.111

0.565 ± 0.087

TC/HDL-c

1.64 ± 0.07

1.68 ± 0.13

1.48 ± 0.17**

1.53 ± 0.14*

1.53 ± 0.15*

Atherogenic index

0.639 ± 0.066

0.685 ± 0.127

0.483 ± 0.167**

0.530 ± 0.145*

0.533 ± 0.146*

  1. All values are means ± SD (n = 10–11)
  2. #p < 0.05 vs. C57BL/6J mice
  3. ##p < 0.01 vs. C57BL/6J mice
  4. *p < 0.05 vs. KKAy mice
  5. **p < 0.01 vs. KKAy mice