Fig. 3

GZ17 is less toxic on non-cancer human islets. a The cell death inducing activity of GZ17 was compared in human prostate cancer spheroids and human non-cancerous islets. GZ17 failed to induce cell death in the human islets, but consistently caused a dramatic loss of cancer cells. *indicates p < 0.01 and ** indicates p < 0.001 when comparing the islet and prostate cancer results at each dose. b The IC50 for vascular smooth muscle cells and human fibroblast cells were compared to the value for prostate cancer cells