Antioxidant activity and hepatoprotective potential of Cedrelopsis grevei on cypermethrin induced oxidative stress and liver damage in male mice

Table 5 The severity of the reaction in liver tissue of different groups according to the histopathological alterations.

Histopathological alterations	Treatment
Histopathological alterations	Con	Ext 150	Ext 300	Cyp	Cyp+ Ext 150	Cyp+ Ext 300
Inflammatory cell infiltration in portal area	-	-	-	+++	-	-
Inflammatory cell infiltration in hepatic parenchyma	-	-	-	+++	-	-
Degeneration in hepatocytes	-	-	-	++++	++	-
Congestion in portal vein	-	-	-	++++	-	++
Congestion in central vein	-	-	-	+++	+	-

Con: control; Cyp: cypermethrin; Ext 150 & Ext 300; 150 and 300 mg/ kg b.wt of C. grevei MeOH extract. ++++ Very sever; +++ Sever; ++ moderate; + mild; - nil

ISSN: 2662-7671