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Table 2 FIC indices combination of fraction F-10 of D. grandiflora leaf extract with ampicillin against MRSA ATCC 43300. Values represent triplicates of three independent experiments

From: Inhibition of penicillin-binding protein 2a (PBP2a) in methicillin resistant Staphylococcus aureus (MRSA) by combination of ampicillin and a bioactive fraction from Duabanga grandiflora

MIC of F-10 (mg/L) MIC of ampicillin in combination (mg/L) aFIC index
0 50 -
1/4 × MIC (188) 0.78 0.25
1/8 × MIC (94) 3.13 0.18
1/16 × MIC (47) 12.5 0.31
1/32 × MIC (23) 12.5 0.28
  1. aFIC index; synergism ≤ 0.5, indifference >0.5 but ≤ 4.0, and antagonism > 4