Fig. 2

Electron microscopic observation on the morphology of M. canis under different medicines or cultivation hours; 1 mg of palmatine or berberine or B-P combination (1 mg + 1 mg) or 400 ug of clotrimazole, DMSO or negative control. The shapes of M. canis in different medicine groups with 18 h were abnormal except DMSO or Negative control group. After 30 h incubation, the degree of damage of M. canis in medicine groups became more serious than 18 h and still there were no changes in DMSO or Negative control group