|
Herb/Drug
|
Extract/Fractions
|
% Clot lysis (mean ± S.D)
|
P-values (two-tailed) when compared to negative control (water)
|
|---|
|
Streptokinase (+ve control)
|
-
|
80.77 ± 1.12**
|
<0.001
|
|
Water (−ve control)
|
-
|
5.69 ± 3.09*
|
<0.05
|
|
Trema orientalis
|
Methanol (crude)
|
47.88 ± 6.12**
|
<0.001
|
|
Chloroform
|
46.44 ± 2.44**
|
<0.001
|
|
n-hexane
|
15.37 ± 0.29
| |
|
Hydro-methanol
|
45.78 ± 3.32**
|
<0.001
|
|
Ethyl acetate
|
43.29 ± 2.98**
|
<0.001
|
|
Bacopa monnieri
|
Methanol (crude)
|
43.38 ± 8.69**
|
<0.001
|
|
Chloroform
|
48.39 ± 10.12
**
|
< 0.001
|
|
n-hexane
|
32.88 ± 10.72*
|
< 0.05
|
|
Hydro-methanol
|
30.73 ± 1.13*
|
< 0.05
|
|
Ethyl acetate
|
27.68 ± 1.34*
|
< 0.05
|
|
Capsicum frutiescens
|
Methanol (crude)
|
27.96 ± 0.50*
|
< 0.05
|
|
Chloroform
|
36.87 ± 1.27*
|
< 0.05
|
|
n-hexane
|
11.23 ± 1.29
| |
|
Hydro-methanol
|
40.29 ± 1.26**
|
< 0.001
|
|
Ethyl acetate
|
19.82 ± 0.49
| |
|
Brassica oleracea
|
Methanol (crude)
|
34.96 ± 4.60*
|
< 0.05
|
|
Chloroform
|
30.24 ± 0.95*
|
< 0.05
|
|
n-hexane
|
18.30 ± 3.55
| |
|
Hydro-methanol
|
43.70 ± 1.97**
|
< 0.001
|
|
Ethyl acetate
|
15.29 ± 11.29
| |
|
Urena sinuata
|
Methanol (crude)
|
39.30 ± 2.87*
|
< 0.05
|
|
Chloroform
|
47.89 ± 6.83**
|
< 0.001
|
|
n-hexane
|
26.58 ± 10.27*
|
< 0.05
|
|
Hydro-methanol
|
29.51 ± 3.62*
|
< 0.05
|
|
Ethyl acetate
|
38.29 ± 2.18*
|
< 0.05
|
- Values are mean ± SD, (n = 5); *P < 0.05, **P < 0.001, Dunnet test as compared to control (positive and negative). Statistical representation of the effective clot lysis percentage by herbal preparations, positive thrombolytic control (Streptokinase) and negative control (sterile distilled water) processed by paired t-test analysis (Dunnet test). Bold text indicates the highest clot lytic activity of chloroform extract of Bacopa monnieri.
