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Table 2 Effect of herbal extracts and their different fractions on in vitro clot lysis

From: Effects of organic extracts and their different fractions of five Bangladeshi plants on in vitro thrombolysis

Herb/Drug Extract/Fractions % Clot lysis (mean ± S.D) P-values (two-tailed) when compared to negative control (water)
Streptokinase (+ve control) - 80.77 ± 1.12** <0.001
Water (−ve control) - 5.69 ± 3.09* <0.05
Trema orientalis Methanol (crude) 47.88 ± 6.12** <0.001
Chloroform 46.44 ± 2.44** <0.001
n-hexane 15.37 ± 0.29  
Hydro-methanol 45.78 ± 3.32** <0.001
Ethyl acetate 43.29 ± 2.98** <0.001
Bacopa monnieri Methanol (crude) 43.38 ± 8.69** <0.001
Chloroform 48.39 ± 10.12 ** < 0.001
n-hexane 32.88 ± 10.72* < 0.05
Hydro-methanol 30.73 ± 1.13* < 0.05
Ethyl acetate 27.68 ± 1.34* < 0.05
Capsicum frutiescens Methanol (crude) 27.96 ± 0.50* < 0.05
Chloroform 36.87 ± 1.27* < 0.05
n-hexane 11.23 ± 1.29  
Hydro-methanol 40.29 ± 1.26** < 0.001
Ethyl acetate 19.82 ± 0.49  
Brassica oleracea Methanol (crude) 34.96 ± 4.60* < 0.05
Chloroform 30.24 ± 0.95* < 0.05
n-hexane 18.30 ± 3.55  
Hydro-methanol 43.70 ± 1.97** < 0.001
Ethyl acetate 15.29 ± 11.29  
Urena sinuata Methanol (crude) 39.30 ± 2.87* < 0.05
Chloroform 47.89 ± 6.83** < 0.001
n-hexane 26.58 ± 10.27* < 0.05
Hydro-methanol 29.51 ± 3.62* < 0.05
Ethyl acetate 38.29 ± 2.18* < 0.05
  1. Values are mean ± SD, (n = 5); *P < 0.05, **P < 0.001, Dunnet test as compared to control (positive and negative). Statistical representation of the effective clot lysis percentage by herbal preparations, positive thrombolytic control (Streptokinase) and negative control (sterile distilled water) processed by paired t-test analysis (Dunnet test). Bold text indicates the highest clot lytic activity of chloroform extract of Bacopa monnieri.