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Table 2 Effects of the MEMM on gastric lesions induced by ethanol in rats pretreated with L- NAME or NEM

From: Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves

Pre-treatment Treatment Dose, mg/kg Ulcer area (mm2)
Saline 10% DMSO - 33.33 ± 1.84
CBX 100 3.17 ± 0.31a
MEMM 500 0.83 ± 0.40a
Quercitrin 250 mg/kg 1.62 ± 0.74a
L-NAME 10% DMSO - 49.38 ± 3.64b
CBX 100 mg/kg 7.00 ± 0.76ce
MEMM 500 mg/kg 5.25 ± 0.98cf
Quercitrin 250 mg/kg 22.48 ± 1.93cg
NEM 10% DMSO - 61.50 ± 4.62b
CBX 100 mg/kg 12.00 ± 2.46dh
MEMM 500 mg/kg 54.33 ± 4.82di
Quercitrin 250 mg/kg 38.85 ± 5.21dj
  1. Values are mean ± SEM (n = 6 rats/group).
  2. One-way ANOVA followed by Student–Newman–Keuls.
  3. a,bData differed significantly (p < 0.05) when compared to the (saline + 10% DMSO)- pretreated group.
  4. cData differed significantly (p < 0.05) when compared to the (L-NAME + 10% DMSO)- pretreated group.
  5. dData differed significantly (p < 0.05) when compared to the (NEM + 10% DMSO)- pretreated group.
  6. e,hData differed significantly (p < 0.05) when compared to the (saline + CBX)-pretreated group.
  7. f,iData differed significantly (p < 0.05) when compared to the (saline + MEMM)-pretreated group.
  8. g,jData differed significantly (p < 0.05) when compared to the (saline + quercitrin)-pretreated group.