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Table 1 Effects of MEMM on the parameters of gastric juice and on gastric wall mucus content obtained from pylorus-ligature rats

From: Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves

Model Treatment Dose, (mg/kg) Gastric juice Gastric wall mucus
Volume (ml) pH Total acidity (meq/l) Free acidity (meq/l) Alcian blueμg/g wet tissue
Pylorus ligation 10% DMSO - 5.83 ± 1.01 1.50 ± 0.09 5427.00 ± 380.40 4367.00 ± 573.30 85.68 ± 13.76
Ranitidine 100 1.63 ± 0.30a 4.41 ± 0.76b 1433.00 ± 92.15c 1500.00 ± 235.20d 241.30 ± 14.11*
MEMM 50 6.50 ± 0.52 1.82 ± 0.12 3100.00 ± 392.30c 2420.00 ± 438.80d 151.26 ± 32. 17*
250 2.58 ± 0.61a 2.43 ± 0.22b 3107.00 ± 458.00c 2040.00 ± 327.60d 354.24 ± 38.71*
500 1.95 ± 0.16a 3.55 ± 0.63b 3105.00 ± 435.2c 933.30 ± 291.90d 422.08 ± 67.73*
Quercitrin 50 4.31 ± 0.74a 2.38 ± 0.23b 4648.00 ± 223.50c 3211.00 ± 261.60d 258.63 ± 17.48*
250 4.72 ± 0.38a 4.43 ± 0.16b 3519.00 ± 380.40c 2367.00 ± 382.80d 407.42 ± 21.76*
  1. a,b,c,d,Data with different superscript differed significantly (p < 0.05) when compared to the 10% DMSO-pretreated group within the respective column.
  2. *Data differed significantly (p < 0.05) when compared to the 10% DMSO-pretreated group within the respective column.