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Table 4 Effect of pantoprazole and lycopene on immunoregulatory cytokines in esophageal tissues of experimental animals

From: Effect of lycopene against gastroesophageal reflux disease in experimental animals

S. No. Treatment IL-1β (pg/ml) IL-6 (pg/ml)
Group-I Sham control (Normal saline,3 ml/kg,p.o) 758.98 ± 30.61*** 17673.16 ± 196.4***
Group-II Esophagitis control (Normal saline,3 ml/kg,p.o) 2595.9 ± 210.93 43429.33 ± 868.9
Group-III Lycopene (50 mg/kg,p.o) 755.68 ± 82.67*** 25878.2 ± 405.1***
Group-IV Lycopene (100 mg/kg,p.o) 788.86 ± 38.19*** 22055.31 ± 779.86***c
Group-V Pantoprazole (30 mg/kg,p.o) 612.98 ± 44.47*** 15611.14 ± 411.82***
  1. Each group contains six animals. Values are represented as mean ± SD. Statistical significance compared to toxic control using one-way ANOVA followed by Bonferroni test (***P < 0.001).
  2. Statistical significance compared between lycopene (50 mg/kg) and lycopene (100 mg/kg) using one-way ANOVA followed by Bonferroni test (c P < 0.001).
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