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Table 3 Associations of FTO rs7193144 (T > C) with determination of So-Eum or Tae-Eum type, after adjusting age, sex, and BMI

From: The obesity-risk variant of FTO is inversely related with the So-Eum constitutional type: genome-wide association and replication analyses

Population SE versus NSE TE versus NTE
MAF (n)    MAF (n)   
SE NSE OR (95% CI) P TE NTE OR (95% CI) P
Stage 1 0.106 (1903) 0.140 (1903) 0.706 (0.514, 0.968) 0.00210 0.135 (1903) 0.114 (1903) 1.097 (0.856, 1.407) 0.466
Stage 2 0.122 (833) 0.146 (835) 0.706 (0.514, 0.967) 0.0308 0.146 (837) 0.119 (831) 1.248 (0.885, 1.762) 0.207
Combined 0.111 (2736) 0.142 (2738) 0.693 (0.572, 0.839) 1.73E-04 0.138 (2740) 0.116 (2734) 1.146 (0.937, 1.402) 0.183
  1. Abbreviations: FTO fat mass and obesity–associated, BMI body mass index,SE So-Eum, NSE non-So-Eum, TE Tae-Eum, NTE non-Tae-Eum, MAF minor allele frequency, OR odds ratio, 95% CI, 95% confidence interval.
  2. Logistic regression analysis with adjustment for age, sex, and BMI in an additive genetic model: (stage 1) genome-wide association analysis in the KoGES population; (stage 2) replication analysis in the KCMS population.
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