Table 2 Time-course effect of TSL1 (0.1 g/kg) on the writhing test in mice
Pre-treatment (h) with TSL1 (0.1 g/kg) | No. of writhes in 30 min/writhing response* | Percentage of inhibition | Pvalue |
|---|---|---|---|
Control | 127.8 ± 13.46 | 0.0 | |
0.0 | 134.8 ± 11.7 | −1.1% | 0.285 |
0.5 | 102.1 ± 22.8 | 20.1% | < 0.05 |
1.0 | 67.8 ± 20.7 | 46.9% | < 0.001 |
2.0 | 85.3 ± 22.6 | 33.3% | < 0.001 |
6.0 | 94.6 ± 14.0 | 25.9% | < 0.001 |