Table 6 Cytotoxicity of OJS in various cell lines
From: Cytotoxicity and sub-acute toxicity in Crl:CD (SD) rats of traditional herbal formula Ojeok-san
Cell line | Origin | Concentration (μg/ml) | |||||
|---|---|---|---|---|---|---|---|
0 | 10 | 20 | 50 | 100 | 200 | ||
SH-SY5Y | Human, Neuroblastoma | 100 ± 1.97 | 100 ± 3.48 | 99 ± 1.74 | 99 ± 3.34 | 98 ± 2.65 | 96 ± 1.55 |
Clone M-3 | Mouse, Melanoma | 100 ± 4.22 | 101 ± 5.59 | 98 ± 3.67 | 100 ± 8.26 | 99 ± 6.17 | 99 ± 10.22 |
SK-N-SH | Human, Neuroblastoma (brain) | 100 ± 2.20 | 105 ± 2.71 | 104 ± 1.66 | 107 ± 3.00 | 105 ± 1.38 | 108 ± 3.09 |
U-373 MG | Human, Glioblastoma (brain) | 100 ± 2.63 | 100 ± 4.28 | 97 ± 1.83 | 95 ± 1.44 | 96 ± 1.67 | 96 ± 4.22 |
U-87 MG | Human, Glioblastoma (brain) | 100 ± 7.07 | 100 ± 2.56 | 96 ± 1.22 | 99 ± 4.13 | 100 ± 3.38 | 100 ± 4.74 |
HEK-293 | Human, Kidney | 100 ± 9.45 | 101 ± 3.50 | 109 ± 4.62 | 106 ± 3.60 | 96 ± 2.86 | 97 ± 3.14 |
HepG2 | Human, Hepatoblastoma | 100 ± 2.67 | 92 ± 3.49 | 93 ± 3.05 | 92 ± 4.92 | 99 ± 2.06 | 87 ± 4.32 |
Hep3B | Human, Hepatocarcinoma | 100 ± 1.95 | 100 ± 2.56 | 101 ± 2.15 | 104 ± 0.51 | 96 ± 3.47 | 93 ± 0.85 |
RAW 264.7 | Mouse, Macrophage | 100 ± 5.72 | 112 ± 9.54 | 121 ± 3.42 | 117 ± 3.59 | 115 ± 1.71 | 113 ± 1.56 |
3T3-L1 | Mouse, Fibroblast (pre-adipocyte) | 100 ± 2.60 | 105 ± 3.71 | 105 ± 2.67 | 110 ± 1.95 | 109 ± 3.04 | 113 ± 4.31 |
HIT-T15 | Hamster, Pancreas | 100 ± 2.83 | 95 ± 15.62 | 97 ± 13.85 | 97 ± 16.78 | 96 ± 8.35 | 95 ± 7.53 |
HL-60 | Human, Leukemia, lymphoblast | 100 ± 1.13 | 100 ± 1.25 | 100 ± 1.50 | 99 ± 1.43 | 100 ± 1.97 | 98 ± 1.99 |
HT-29 | Human, Colon cancer cell | 100 ± 2.78 | 102 ± 1.36 | 121 ± 2.55 | 99 ± 1.79 | 102 ± 3.45 | 104 ± 4.85 |
NIH-3T3 | Mouse, Fibroblast | 100 ± 6.28 | 102 ± 5.43 | 103 ± 5.32 | 102 ± 6.82 | 105 ± 9.97 | 104 ± 5.99 |
B16F10 | Mouse, Melanoma | 100 ± 8.87 | 91 ± 2.43 | 91 ± 5.50 | 94 ± 3.17 | 98 ± 6.68 | 111 ± 3.72 |
MCF-7 | Human, Breast cancer | 100 ± 4.84 | 114 ± 11.1 | 114 ± 0.44 | 114 ± 4.23 | 110 ± 8.76 | 110 ± 4.33 |
HaCaT | Human, Keratinocyte | 100 ± 1.55 | 98 ± 1.67 | 98 ± 1.00 | 99 ± 3.21 | 97 ± 3.81 | 102 ± 2.99 |
PC12 | Rat, Adrenal medulla, pheochromocytoma | 100 ± 1.28 | 102 ± 1.71 | 96 ± 1.54 | 98 ± 2.94 | 98 ± 2.12 | 93 ± 3.20 |
AGS | Human, Gastric adenocarcinoma | 100 ± 1.31 | 99 ± 1.94 | 100 ± 3.8 | 94 ± 10.36 | 96 ± 1.83 | 100 ± 1.80 |
BEAS-2B | Human, Bronchial epithelial, normal cell | 100 ± 2.00 | 102 ± 0.86 | 101 ± 1.24 | 101 ± 0.65 | 104 ± 3.42 | 105 ± 2.68 |
LNCaP | Human, Prostate cancer | 100 ± 9.14 | 101 ± 5.75 | 102 ± 8.88 | 101 ± 7.03 | 102 ± 12.51 | 98 ± 6.86 |
RBL-1 | Rat, Basophilic leukemia | 100 ± 5.97 | 102 ± 9.42 | 102 ± 6.60 | 102 ± 1.80 | 103 ± 2.12 | 102 ± 0.58 |
NRK52 | Rat, Kidney | 100 ± 1.19 | 100 ± 1.19 | 99 ± 2.18 | 102 ± 1.01 | 102 ± 3.99 | 106 ± 2.65 |