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Table 6 Cytotoxicity of OJS in various cell lines

From: Cytotoxicity and sub-acute toxicity in Crl:CD (SD) rats of traditional herbal formula Ojeok-san

Cell line Origin Concentration (μg/ml)
0 10 20 50 100 200
SH-SY5Y Human, Neuroblastoma 100 ± 1.97 100 ± 3.48 99 ± 1.74 99 ± 3.34 98 ± 2.65 96 ± 1.55
Clone M-3 Mouse, Melanoma 100 ± 4.22 101 ± 5.59 98 ± 3.67 100 ± 8.26 99 ± 6.17 99 ± 10.22
SK-N-SH Human, Neuroblastoma (brain) 100 ± 2.20 105 ± 2.71 104 ± 1.66 107 ± 3.00 105 ± 1.38 108 ± 3.09
U-373 MG Human, Glioblastoma (brain) 100 ± 2.63 100 ± 4.28 97 ± 1.83 95 ± 1.44 96 ± 1.67 96 ± 4.22
U-87 MG Human, Glioblastoma (brain) 100 ± 7.07 100 ± 2.56 96 ± 1.22 99 ± 4.13 100 ± 3.38 100 ± 4.74
HEK-293 Human, Kidney 100 ± 9.45 101 ± 3.50 109 ± 4.62 106 ± 3.60 96 ± 2.86 97 ± 3.14
HepG2 Human, Hepatoblastoma 100 ± 2.67 92 ± 3.49 93 ± 3.05 92 ± 4.92 99 ± 2.06 87 ± 4.32
Hep3B Human, Hepatocarcinoma 100 ± 1.95 100 ± 2.56 101 ± 2.15 104 ± 0.51 96 ± 3.47 93 ± 0.85
RAW 264.7 Mouse, Macrophage 100 ± 5.72 112 ± 9.54 121 ± 3.42 117 ± 3.59 115 ± 1.71 113 ± 1.56
3T3-L1 Mouse, Fibroblast (pre-adipocyte) 100 ± 2.60 105 ± 3.71 105 ± 2.67 110 ± 1.95 109 ± 3.04 113 ± 4.31
HIT-T15 Hamster, Pancreas 100 ± 2.83 95 ± 15.62 97 ± 13.85 97 ± 16.78 96 ± 8.35 95 ± 7.53
HL-60 Human, Leukemia, lymphoblast 100 ± 1.13 100 ± 1.25 100 ± 1.50 99 ± 1.43 100 ± 1.97 98 ± 1.99
HT-29 Human, Colon cancer cell 100 ± 2.78 102 ± 1.36 121 ± 2.55 99 ± 1.79 102 ± 3.45 104 ± 4.85
NIH-3T3 Mouse, Fibroblast 100 ± 6.28 102 ± 5.43 103 ± 5.32 102 ± 6.82 105 ± 9.97 104 ± 5.99
B16F10 Mouse, Melanoma 100 ± 8.87 91 ± 2.43 91 ± 5.50 94 ± 3.17 98 ± 6.68 111 ± 3.72
MCF-7 Human, Breast cancer 100 ± 4.84 114 ± 11.1 114 ± 0.44 114 ± 4.23 110 ± 8.76 110 ± 4.33
HaCaT Human, Keratinocyte 100 ± 1.55 98 ± 1.67 98 ± 1.00 99 ± 3.21 97 ± 3.81 102 ± 2.99
PC12 Rat, Adrenal medulla, pheochromocytoma 100 ± 1.28 102 ± 1.71 96 ± 1.54 98 ± 2.94 98 ± 2.12 93 ± 3.20
AGS Human, Gastric adenocarcinoma 100 ± 1.31 99 ± 1.94 100 ± 3.8 94 ± 10.36 96 ± 1.83 100 ± 1.80
BEAS-2B Human, Bronchial epithelial, normal cell 100 ± 2.00 102 ± 0.86 101 ± 1.24 101 ± 0.65 104 ± 3.42 105 ± 2.68
LNCaP Human, Prostate cancer 100 ± 9.14 101 ± 5.75 102 ± 8.88 101 ± 7.03 102 ± 12.51 98 ± 6.86
RBL-1 Rat, Basophilic leukemia 100 ± 5.97 102 ± 9.42 102 ± 6.60 102 ± 1.80 103 ± 2.12 102 ± 0.58
NRK52 Rat, Kidney 100 ± 1.19 100 ± 1.19 99 ± 2.18 102 ± 1.01 102 ± 3.99 106 ± 2.65