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Table 7 Exact MICs (μg/ml) of flavonoid/(s) with antibiotics against S. aureus (ATCC 43300) and clinical isolates of MRSA

From: Antibiotic additive and synergistic action of rutin, morin and quercetin against methicillin resistant Staphylococcus aureus

  With (M + R) With Q With (M + R) + Q
AMO† 340 260 (140)+ 80
AMO* 367.40 ± 15.71 279.00a ± 14.65 (163.56a) ±16.75 + 103.56a ± (15.99)
MIC range* 340 - 380 260 - 320 M + R = 140 – 200; Q = 80 – 140
AMP† 400 160 (160)+ 80
AMP* 427.40a ± 14.40 178.80a ± 14.25 (186.56a) ± 15.80 + 112.37a ± 16.42
MIC range* 400 - 440 160 - 200 M + R = 160–220; Q = 80 – 140
CEPH† 340 160 (140)+ 60
CEPH* 367.40 ± 15.71 178.80a ± 14.25 (163.56a) ± 16.52 + 83.56a ±15.02
MIC range* 340 - 380 160 - 200 M + R = 140 – 200; Q = 60 – 120
CET † 320 140 (140) +40
CET* 347.40 ± 12.92 158.60a ± 15.11 (162.94a) ± 16.98+ 65.94 a ± 16.9
MIC range* 320 - 360 140 - 180 M + R = 140 – 180; Q = 40 -100
IMP† 300 120 (120) +40
IMP* 327.80a ± 14.85 138.80a ± 14.99 (148.31a) ± 19.59+ 66.56a ±16.50
MIC range* 300 - 340 120 - 160 M + R = 120–180 ; Q = 40 – 100
ME† 360 180 180 + 80
ME* 387.40 ± 15.78 196.70a ± 12.75 (208.51a) ± 19.98 + 88.51a ±19.80
MIC range* 360 - 400 180 - 220 M + R = 180 – 240; Q = 80-160
  1. MIC of M & R is same.
  2. a= Average value.
  3. *against MRSA clinical isolates (n = 100).
  4. † against S. aureus (ATCC 43300).