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Table 3 The Network objects and its functions

From: In-silico prediction of drug targets, biological activities, signal pathways and regulating networks of dioscin based on bioinformatics

No Species Gene Name Network Objects Protein Function
1 Homo sapiens ACPP PPAP Protein phosphatase
2 Homo sapiens ADK Adenosine kinase Generic kinase
3 Homo sapiens ARL5A ARL5 RAS superfamily
4 Homo sapiens BACE1 BACE1 Generic protease
5 Homo sapiens C3 C3 Generic binding protein
    C3a Generic binding protein
    C3b Generic binding protein
    C3c Generic binding protein
    C3dg Generic binding protein
    C5 convertase (C2aC4bC3b) Generic protease
    C5 convertase (C3bBb) Generic protease
    iC3b Generic binding protein
6 Homo sapiens CALM1 Calmodulin Generic binding protein
7 Homo sapiens CALM2 Calmodulin Generic binding protein
8 Homo sapiens CALM3 Calmodulin Generic binding protein
9 Homo sapiens CCNA2 Cyclin A Generic binding protein
    Cyclin A2 Generic binding protein
10 Homo sapiens CDK2 CDK2 Protein kinase
11 Homo sapiens CES1 CES1 Generic enzyme
12 Homo sapiens EGF EGF Receptor ligand
13 Homo sapiens EGFR EGFR Receptor with enzyme activity
14 Homo sapiens FBXW7 Cul1/Rbx1 E3 ligase Generic enzyme
    FBXW7 Generic binding protein
    Skp2/TrCP/FBXW Generic binding protein
15 Homo sapiens FNTA FTase Generic enzyme
    FTase-alpha Generic enzyme
    GGTase-I Generic enzyme
16 Homo sapiens FNTB FTase Generic enzyme
    FTase-beta Generic enzyme
17 Homo sapiens GLO1 Glyoxalase I Generic enzyme
18 Homo sapiens GSTA1 GSTA1 Generic enzyme
19 Homo sapiens HBA1 Adult hemoglobin Generic protein
    Alpha1-globin Transporter
    HP/HB complex Generic protein
20 Homo sapiens HBA2 Adult hemoglobin Generic protein
    Alpha1-globin Transporter
    HP/HB complex Generic protein
21 Homo sapiens HBB Adult hemoglobin Generic protein
    HBB Transporter
    HP/HB complex Generic protein
22 Homo sapiens HPGDS PGDS Generic enzyme
23 Homo sapiens KIF11 KNSL1 Generic binding protein
24 Homo sapiens NCBP1 CBP80 Generic binding protein
25 Homo sapiens NCBP2 CBP20 Generic binding protein
26 Homo sapiens NUP98 NUP98 Generic channel
    NUP98/HHEX fusion protein Transcription factor
    NUP98/HOXA9 fusion protein Transcription factor
    Nuclear pore complex proteins Generic channel
27 Homo sapiens PAPSS2 PAPSS2 Generic kinase
28 Homo sapiens PDE5A PDE Generic protein
    PDE5A Generic enzyme
29 Homo sapiens PIK3CG PI3K cat class IB (p110-gamma) Lipid kinase
30 Homo sapiens POLL DNA polymerase lambda Generic enzyme
31 Homo sapiens PPIA Cyclophilin A Generic enzyme
32 Homo sapiens PPP3CA Calcineurin A (alpha) Protein phosphatase
    Calcineurin A (catalytic) Protein phosphatase
33 Homo sapiens PPP3R1 Calcineurin B (regulatory) Generic binding protein
    Calcineurin B1 Generic binding protein
34 Homo sapiens PYGL Glycogen phosphorylase Generic enzyme
    PYGL Generic enzyme
35 Homo sapiens RAC3 Rac3 RAS superfamily
36 Homo sapiens SNRPA SNRPA Generic binding protein
37 Homo sapiens TK1 TK1 Generic kinase
38 Homo sapiens TOP1 TOP1 Generic enzyme
39 Homo sapiens UPF1 RENT1 Generic binding protein
1 Rattus norvegicus Ctsb Cathepsin B Generic protease
2 Rattus norvegicus Fnta FTase Generic enzyme
    FTase-alpha Generic enzyme
    GGTase-I Generic enzyme
3 Rattus norvegicus Fntb FTase Generic enzyme
    FTase-beta Generic enzyme
4 Rattus norvegicus Grm1 Galpha(q)-specific metabotropic glutamate GPCRs Generic receptor
    mGluR1 GPCR
5 Rattus norvegicus Nos1 nNOS Generic enzyme
1 Mus musculus Gsta1 Gsta1 (mouse) Generic enzyme
2 Mus musculus H2-D1 HLA-B Generic receptor
    MHC class I Generic receptor
3 Mus musculus H2-Ea HLA-DRA1 Generic receptor
    MHC class II Generic receptor
    MHC class II alpha chain Generic receptor
4 Mus musculus H2-Ea HLA-DRA1 Generic receptor
    MHC class II Generic receptor
    MHC class II alpha chain Generic receptor
5 Mus musculus H2-L H-2 L(d) Generic receptor
    HLA-C Generic receptor
    MHC class I Generic receptor
6 Mus musculus Nos2 iNOS Generic enzyme
7 Mus musculus OTTMUSG00000015050 Trav9d-4 Generic receptor
8 Mus musculus Polm DNA polymerase mu Generic enzyme
9 Mus musculus Tpmt Thiopurine S-methyltransferase Generic enzyme
10 Mus musculus Uap1 UAP1 Generic enzyme