Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in mice

Table 8 Effect of leaf extract of P. hydropiper extract on involvement of ATP-sensitive K ⁺ channel pathway

Treatment	Dose (mg/kg)	Number of writhing	Inhibition (%)
Control	0.1 ml/mouse	64.7 ± 2.96	-
Glibenclamide (GB)	10	57.4 ± 2.02	11.28
MEPH + GB	25 + 10	29.6 ± 2.31*	54.25
MEPH + GB	50 + 10	25.7 ± 2.59*	60.28
MEPH + GB	75 + 10	22.5 ± 4.33*	65.22

Each value is presented as the Mean ± SEM (n = 5). MEPH = Methanolic extract of P. hydropiper leaves.
*p < 0.001 compared with the control group (Dunnett’s test).

ISSN: 2662-7671