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Table 8 Effect of leaf extract of P. hydropiper extract on involvement of ATP-sensitive K + channel pathway

From: Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in mice

Treatment Dose (mg/kg) Number of writhing Inhibition (%)
Control 0.1 ml/mouse 64.7 ± 2.96 -
Glibenclamide (GB) 10 57.4 ± 2.02 11.28
MEPH + GB 25 + 10 29.6 ± 2.31* 54.25
MEPH + GB 50 + 10 25.7 ± 2.59* 60.28
MEPH + GB 75 + 10 22.5 ± 4.33* 65.22
  1. Each value is presented as the Mean ± SEM (n = 5). MEPH = Methanolic extract of P. hydropiper leaves.
  2. *p < 0.001 compared with the control group (Dunnett’s test).