Inhibited effect of EAC-B to tumor growthin vivo. (A) BALB/c nude mice were sacrificed at the 21st days after subcutaneous injection of MGC-803 cells (2 × 106/mouse) followed by treatment. The treatment included of PBS (control), CTX (cyclophosphamide, peritoneal injection), EAC-B of 0.2, 1 and 5 g/kg (intragastric infusion). The scatter diagrams represented the tumor weight of each female and male animal. Significant difference were labelled with asterisk (p < 0.05) compared to PBS groups. (B) Histological change of the tumor tissue by HE staining (×20 of magnification). The loss of tumor cells (arrows) indicated necrosis (right).